Explanation of how to administer medication

Ovulation induction

Ovulation induction is a treatment used for women who have difficulty becoming pregnant because their cycle is irregular or absent altogether. 

No pregnancy
Irregular cycle
PCOS
Hormonal abnormalities
The treatment consists of the following steps:
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Intake

Based on the results of the initial fertility assessment , you and your doctor will decide on the best next step to increase your chances of pregnancy.

For women with an irregular cycle, we first look further into the possible cause of the irregular or absent cycle. If being overweight plays a role, the doctor will advise you to lose weight first. In some cases, weight loss can make the menstrual cycle more regular again by itself, allowing ovulation to start as well.

In some cases, natural ovulation then becomes possible again without the need for medication. Losing weight also increases the chance of a healthy pregnancy.

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Medication

Starting treatment
Treatment usually starts on the third day of your menstrual cycle. As soon as your period starts, please phone us. Sometimes it is necessary to induce a period with medication first. Does the first day of your cycle fall at the weekend? Then email us or call us on Monday morning – there is no need to use the emergency line.

Medication
Depending on your situation, you will receive medication in the form of:

  • Tablets (e.g. letrozole or clomifene citrate) – These tablets stimulate your body to produce FSH itself.
  • Injections with hormones (e.g. FSH injections Gonal-f or Ovaleap) – These FSH injections stimulate the ovaries to grow follicles.

The aim of this medication is to stimulate the ovaries so that one follicle matures. Sometimes more than one follicle grows. We monitor this closely using ultrasound. 

Read more about the medicationhere.

 

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Monitoring

During the treatment cycle, we use transvaginal ultrasound scans to monitor closely whether the ovaries are responding to the medication. The first scan usually takes place around day 10 of the cycle. We check whether one or more follicles are growing and whether the endometrium is building up properly.

  • No dominant follicle? If no dominant follicle is visible at the first scan, we repeat the scan every few days, up to cycle day 21 at the latest. If no follicle has grown by then, the doctor may decide to increase the dose of tablets in the next cycle. If that does not help, switching to stimulation with FSH injections is usually the next step. 
  • Progesterone check: During the first treatment, we also check whether ovulation has actually taken place. About eight days after a positive ovulation test, we take a single blood test to measure your progesterone level. If this level is high enough, we know for certain that ovulation has occurred.

These checks help us tailor the treatment optimally to your body.

Explanation of how to administer medication
Triggering ovulation

When the scan shows that a follicle is large enough (usually around 18–20 mm, sometimes slightly larger due to the medication), we determine the right moment for ovulation. This can be done in two ways:

  • Spontaneous ovulation: Sometimes ovulation occurs by itself. You can then use ovulation tests at home to detect the LH surge. Based on this, we advise you on the best moment for intercourse or insemination.
  • Triggering ovulation with an hCG injection: In other cases, your doctor decides to trigger ovulation with an injection of the hormone hCG. This injection mimics the natural LH surge, causing the egg to mature fully and ovulation to start. The timing of the injection is carefully determined based on the scans. Ovulation usually follows about 36 to 40 hours after the injection. You can plan intercourse accordingly. 

The medication is prescribed via the Serphaportal, where you can also find the package leaflets and clear injection instructions .

Egg retrieval
Intercourse or IUI

Around the time of ovulation, we advise you on the best time to have intercourse. In some cases, an insemination takes place (IUI).

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After ovulation

Sometimes medication is prescribed after ovulation to support the endometrium, such as progesterone in the form of vaginal capsules. We only do this when there is an indication for it.

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Waiting

About two weeks after ovulation, you take a pregnancy test using your first morning urine. An exciting moment! Let us know the result as soon as you have it.

Positive test – Pregnant
Congratulations! If your test is positive, we will schedule an ultrasound scan at around 7 to 8 weeks of pregnancy. If the scan shows a well-growing embryo with a beating heart in your womb, the treatment has been successful. We will then refer you to a midwife of your choice for the rest of your pregnancy care. In some cases, a referral to a gynaecologist is needed. We would love to hear how your pregnancy and the birth go. Read more.

Negative test – Not pregnant
A negative test, a scan showing no pregnancy or the start of your period is, of course, disappointing. You will discuss the next steps together with the doctor. When your period starts, please contact us on the first day of your period to start a new IUI treatment. If you are not sure whether it is your period, please check with us, especially if you are taking medication for the treatment.

FAQ

Frequently asked questions

You will find answers to our frequently asked questions alongside. Can't find your answer? Please feel free to contact us.
Does ovulation induction hurt?
How many ovulation induction treatments are needed?
How long after a positive ovulation test do I ovulate?
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Waiting times

Reception and waiting area Nij Clinics Gorinchem

We attach great importance to a quick and efficient start to your treatment. We understand that waiting for care can be difficult, which is why we want to keep you as well informed as possible about the current waiting times. View the current overview of waiting times. 

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